Aurora kinase - mTOR signaling in sarcomatoid mRCC
نویسندگان
چکیده
Department of Medical Oncology & Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA Department of Molecular Pharmacology, City of Hope Comprehensive Cancer Center, Duarte, CA Department of Pathology, City of Hope Comprehensive Cancer Center, Duarte, CA Department of Biostatistics, City of Hope Comprehensive Cancer Center, Duarte, CA Department of Surgery, City of Hope Comprehensive Cancer Center, Duarte, CA Functional Genomics, City of Hope Comprehensive Cancer Center, Duarte, CA Department of Pathology, Dana Farber Cancer Center, Boston, MA Department of Medical Oncology, Dana Farber Cancer Center, Boston, MA Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX
منابع مشابه
RNA-seq reveals aurora kinase-driven mTOR pathway activation in patients with sarcomatoid metastatic renal cell carcinoma.
UNLABELLED Sarcomatoid metastatic renal cell carcinoma (mRCC) is associated with a poor prognosis, and the biology of the disease has been inadequately characterized. RNA sequencing (RNA-seq) was performed on adjacent benign, clear cell, and sarcomatoid components from clinical specimens with sarcomatoid mRCC. M phase and cell-cycle pathways were enriched in sarcomatoid versus adjacent clear ce...
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تاریخ انتشار 2014